BMS-906024 (R) Smiles: C[C@H]1CO[C@]2(CC1)O[C@H]1C[C@H]3[C@@H]4CC=C5C[C@H](CC[C@]5(C)[C@H]4CC[C@]3(C)[C@H]1[C@@H]2C)O[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O

Smiles: C[C@H]1CO[C@]2(CC1)O[C@H]1C[C@H]3[C@@H]4CC=C5C[C@H](CC[C@]5(C)[C@H]4CC[C@]3(C)[C@H]1[C@@H]2C)O[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O

28)/t13-/m1/s1

2077980-83-5

approximately 100-fold better than that of genistein

BMS-906024 (R) Smiles: C[C@H]1CO[C@]2(CC1)O[C@H]1C[C@H]3[C@@H]4CC=C5C[C@H](CC[C@]5(C)[C@H]4CC[C@]3(C)[C@H]1[C@@H]2C)O[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1OBMS 906024 is an orally active and selective secretase (gamma secretase) inhibitor. BMS 906024 is a potent pan Notch receptors inhibitor with IC50s of 1. 6 nM, 0. 7 nM, 3. 4 nM, and 2. 9 nM for Notch1, 2, 3, and 4 receptors, respectively. BMS 906024 demonstrates broad spectrum antineoplastic activity. Product information CAS Number: 1401066 79 2 Molecular Weight: 556. 50 Formula: C26H26F6N4O3 Chemical Name: (2R,3S) N [(3S) 1 methyl 2 oxo 5 phenyl 2,3